Conjugated Linoleic Acid - 60 Softgels - Douglas Laboratories
[DL-98336]

Healthy Support for Weight Management

DESCRIPTION
CLA capsules, offered by Douglas Laboratories, provide a significant amount of conjugated linoleic acid, together with an extract of organically grown green tea for maximum stabilization. CLA is thought to be an effective modulator of metabolism, reducing body fat and increasing muscle mass.

FUNCTIONS
CLA is a mixture of conjugated dienoic derivatives of linoleic acid from safflower oil. Conjugated linoleic acid is found mainly in meat and dairy foods; however it can also be found in certain vegetable oils. Its presence in human tissue comes not only from dietary sources, but also from in vivo oxidation of linoleic acid. Although CLA¡¦s activity as a potent metabolic modulator was first recognized in studies of its anticarcinogenic properties in fried hamburger, research of its metabolic activity has now expanded to include its ability to modulate lipid and energy
metabolism, particularly control of body fat and muscle, as well as atherosclerosis.
Research in several animal models has demonstrated that CLA reduces body fat accumulation. Some studies have shown that the reduction in body fat occurs regardless of whether the diet is high or low in fat. It appears that increased energy expenditure is responsible for the decreased fat accumulation. Researchers have observed an increase in fat oxidation, but not a decrease in fat biosynthesis. Mice fed a high fat diet with 1% CLA exhibited a 50% reduction in weights of adipose depots, but no significant effects on body weight or energy intake. Energy expenditure persistently increased almost 8% through the trial period. This chronic increase in metabolic rate is thought to be responsible for the Uncoupling protein gene expression in the mice¡¦s brown fat may be partially responsible for this increased metabolic rate. CLA¡¦s antiobesity effects have also been suggested to involve an inhibition and/or apoptosis of (pre)adipocytes.

INDICATIONS
CLA capsules may be a useful dietary supplement for those who wish to support their weight control efforts.

FORMULA
Two Capsules Contain:

Conjulite. Conjugated Linoleic Acid 680 mg
Polyphenon 60 (Green tea extract) 0.5 mg

SUGGESTED USE
Adults take 2 capsules daily with a meal, or as directed by physician.

SIDE EFFECTS
No adverse effects have been reported.

STORAGE
Store in a cool, dry place, away from direct light. Keep out of reach of children.